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Adult mesenchymal stem cells (MSCs)
Platelet-rich plasma (PRP).
Together, they are revolutionizing the way we approach knee osteoarthritis.
About Osteoarthritis
Osteoarthritis (OA) is a degenerative joint disease in which the protective cartilage that protects the ends of bones wears away. Knees are especially vulnerable. When degenerated, bone sticks to bone, causing pain, swelling and stiffness.
Adult Mesenchymal Stem Cells
MSCs are powerful cells that have the ability to differentiate into many cell types, including bone, cartilage, and muscle. Present in many different tissues such as bone marrow and fat, these stem cells are capable of the following:
Differentiation
They can transform into chondrocytes, the main cells found in healthy cartilage, contributing to cartilage regeneration.
Regulation of the immune response:
By reducing inflammation and modulating the immune response, MSCs create an environment conducive to healing.
The Power of Platelet-Rich Plasma
PRP is derived from a person’s blood. After blood is drawn, it is centrifuged to concentrate platelets.
Growth Factors:
PRP contains a full spectrum of growth factors that promote cell proliferation and tissue repair.
Reduction of Inflammation:
PRP has anti-inflammatory properties, which are important for treating the inflammatory component of osteoarthritis.
In Combination
When MSCs and PRP are combined together, they create a synergistic effect – one which is greater than the sum of their individual benefits.
Improvement of MSC Survival:
PRP provides a favorable environment for MSCs, improving their viability and function.
Stimulation of Cartilage Regeneration:
Thanks to PRP growth factors and the ability of MSCs to differentiate into chondrocytes, there is a concerted effort to regenerate lost cartilage.
Joint Lubrication:
The combination may increase the production of synovial fluid, the knee’s natural lubricant, reducing friction and pain.
For Patients
This therapy offers a minimally invasive and revolutionary approach for people with knee osteoarthritis.
Benefits:
Pain Relief:
Many patients report reduced pain levels after treatment.
Improved portability:
As cartilage regenerates and inflammation subsides, movement may become easier.
Reduction of Drug Dependence:
With improved knee function, there may be less need for pain relievers or other medications.
The combination of Mesenchymal Stem Cells and Platelet-Rich Plasma offers an exciting direction in the management of knee osteoarthritis. It highlights the beauty of using the body’s own mechanisms to heal, combining nature’s wisdom with medical innovation. For those who dream of pain-free walks and dance-filled nights, this could certainly be the ray of hope they’ve been quietly seeking.
